S3:E4 - "Asta La Vista, Baby" - The Aminator
Patrick Fier and Suhon Kim join the pod to share their lates collaboration on a new C-N cross-coupling protocol which leverages a novel multifunctional template reagent. The work emerged from a side-project that started many years ago on the creation of the "Aminator" reagent which inspired the latest reaction. The couplings have very broad scope and Suhong and Patrick explain their motivation for pursuing the work and insights about the reaction enabled by this reagent. We learned a lot on this episode, and we hope you do too!
Read the papers we discussed today:
Transition-Metal-Free C–N Cross-Coupling Enabled by a Multifunctional Reagent - JACS
A Multifunctional Reagent Designed for the Site-Selective Amination of Pyridines - JACS
Follow the Pharm to Table podcast on Twitter - @PharmtoTablePod
Visit our website at https://podcasters.spotify.com/pod/show/pharm-to-table
2024-04-22
21 min
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