#029 Jed Fahey, Sc.D. on Isothiocyanates, the Nrf2 Pathway, Moringa & Sulforaphane Supplementation
Dr. Jed Fahey is a multi-decade veteran of isothiocyanate research and is the director of the Cullman Chemoprotection Center at Johns Hopkins University.
In this episode, you'll discover:
- (00:00) Introduction
- (03:44) What is sulforaphane?
- (10:25) The NRF2 pathway, a master regulator of antioxidants
- (14:22) Cruciferous vegetables are rich sources of sulforaphane
- (20:39) Does cooking broccoli destroy sulforaphane?
- (26:00) Sulforaphane supplements vary widely in quality
- (36:41) Antibiotics wipe out sulforaphane-producing bacteria in the gut
- (46:44) Managing Helicobacter pylori growth with a sulforaphane-rich diet
- (56:15) Sulforaphane reduces inflammation, but does it extend lifespan?
- (01:11:31) The therapeutic potential of sulforaphane for autism spectrum disorders, Alzheimer's disease, and schizophrenia
- (01:22:44) Research challenges and clinical trials
- (01:30:51) Is sulforaphane an anti-depressant?
- 01:34:50 - Moringin from moringa may be an alternative to sulforaphane with similar bioaction
- (01:53:55) How to maximize sulforaphane conversion
- (02:13:27) Testing the anticancer power of sulforaphane
If you're interested in learning more, you can read the full show notes here.
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