66. From miniskirts to stem cell therapy: How a fashion leader is changing heart failure treatment | Jenifer Rosenberg OBE

How do you turn a bold idea into a national institution that changes lives?

In this episode of All About Business, James speaks with Jenifer Rosenberg OBE, entrepreneur in fashion and social impact leader, about building purpose-driven organisations that create lasting change.

Jenifer shares her journey from spotting a gap in support for families facing serious illness, to co-founding Heart Cells Foundation and growing it from a kitchen-table startup into a nationally recognised charity. She reflects on navigating funding challenges, building credibility with clinicians and policymakers, and leading through the emotional realities of mission-led work.

The conversation explores scaling a purpose-driven organisation sustainably, balancing commercial discipline with social impact, and the importance of governance, partnerships, and long-term strategy. Jenifer also shares lessons from stepping back from founder leadership, earning an OBE, and staying resilient while driving systemic change.

A thoughtful conversation about entrepreneurship with purpose, leading with conviction, and building something that truly lasts.

Timestamps

02:18 From post room to senior role

08:07 Quality and innovation with Marks & Spencer

16:28 Branching out into fashion

26:40 The power of innovation

30:23 A personal journey with heart failure

35:24 Founding the Heart Cells Foundation

48:37 Maintaining energy and health

Links

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Find out more the Heart Cells Foundation here:

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